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saponin, dan tanin yang memiliki aktifitas antibakteri, memacu pembentukan&#13;
kolagen dan sebagai astringen. Menurut Dian Reni Agustina (2011) Kombinasi&#13;
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tanaman dapat terjadi efek sinergis dan aditif sebagai pengobatan luka pada&#13;
penderita diabetes. &#13;
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merah (Piper crocatum Ruiz. and Puv.) dan herba pegagan (Centella asiatica L.&#13;
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konsentrasi Carbopol 940 yang digunakan pada formula I adalah 1%, pada&#13;
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meliputi pH, viskositas, homogenitas, daya sebar, warna dan bau. Pengujian&#13;
dilakukan selama 28 hari penyimpanan. &#13;
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mengalami penurunan sedangkan daya sebar mengalami peningkatan. Partikel&#13;
terdistribusi secara merata serta memiliki warna dan bau yang stabil. Ketiga&#13;
formula tidak menimbulkan iritasi kulit saat diaplikasikan ke kulit. &#13;
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Puv.) dan herba pegagan (Centella asiatica L. Urban) dapat diformulasikan&#13;
menjadi sediaan gel yang stabil dan memenuhi persyaratan. Formula yang paling&#13;
stabil adalah formula II dengan konsentrasi Carbopol 940 sebesar 1,5%. &#13;
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crocatum Ruiz. and Puv.), Herba Pegagan (Centella asiatica L. Urban) </text>
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